Polynucleotides are chosen when the goal is deep skin repair and regeneration rather than volume or reshaping. These injectable biostimulators are derived from purified DNA fragments that stimulate fibroblast activity, promote tissue repair and improve hydration at a cellular level. They're particularly effective for skin that has lost its resilience — whether from ageing, sun damage or scarring.
Unlike hyaluronic acid fillers, polynucleotides don't add volume. Instead, they work by improving the skin's own regenerative capacity, making them a good option for patients wanting genuine skin quality improvement from within.


Polynucleotides are injected into the treatment area using fine needles or a cannula, depending on the area and technique. The product integrates into the tissue and stimulates fibroblast activity — the cells responsible for producing collagen and elastin. Your clinician tailors the injection pattern and depth to your specific concerns. A course of 2–3 sessions is typically recommended, spaced 3–4 weeks apart.
